Representing one of the most versatile and abundant drug metabolizing enzymes in humans, cytochrome P450 3A4 (CYP3A4) catalyzes oxidative biotransformation of over 50% of pharmaceuticals. Initial characterization began in the 1980s when cDNA isolation revealed a heme-containing monooxygenase selectively concentrated in human liver showing similarity to rat P450 forms.

ELISA kit information:

• Reactivity: Human
• Sample Type: Plasma, Tissue Homogenates, Serum, Biological Fluids
• Sensitivity: 46.875 pg/ml
• Target: CYP3A4, Cytochrome P450 3A4, CYP3A3, Nifedipine, Albendazole Monooxygenase